Human papilloma viruses infect the stratified squamous epithelia of skin and mucous membranes, where they cause benign lesions, some of which have the potential to progress to invasive cancer. Human papilloma viruses are small, nonenveloped viruses. To establish infection, microtrauma or erosion of the overlying epithelial layers is thought to enable human papilloma viruses to infect cells of the basal epithelial layer, where the stem cells and other long-lived cells are found.
The benign lesions induced by the human papilloma viruses include nongenital and anogenital skin warts, oral and laryngeal papillomas, and anogenital mucosal condylomata. Anogenital infections are almost always transmitted sexually. Long-term infection by a subset of human papilloma viruses can lead to malignant anogenital tumors, including cancers of the anus, penis, vulva, vagina, and cervix. A proportion of oral cancer is also attributable to HPV.
In addition, human papilloma virus infection causes virtually all cases of cervical cancer, the second most common cause of death from cancer among women in the world. Vaccines have an excellent safety profile, are highly immunogenic, and can confer complete type-specific protection against persistent infection and associated lesions in fully vaccinated women. But vaccines are not useful at all for those already affected with warts.
HPV infections tend to last months or years because the viral genome successfully parasitizes these cells and because the virus evades the immune system by limiting most viral gene expression and viral replication to suprabasal cell layers. Most infections are self-limited, presumably because the host eventually mounts a successful immune response.
Cryotherapy, which uses a very cold liquid to freeze a wart, is the most commonly used procedure that does not involve medicine to treat warts. This procedure poses little risk of scarring but can be painful. Tape occlusion, in which you use tape to cover the wart for a period of time, usually takes one to two months to remove the wart.
Surgery is an option if home treatment and treatment at your doctor’s office has failed. Surgery for warts is usually quick and effective. No single surgical method is more effective than another one in curing warts. Generally, doctors start with the surgical method that is least likely to cause scarring. The most common types of surgical treatment for wart removal include electrosurgery, curettage, and laser surgery.
Electrosurgery is burning the wart with an electrical current. Curettage is cutting the wart off with a sharp knife or a small, spoon-shaped tool. The two procedures are often used together. Laser surgery burns off the wart with an intense beam of light. For electrosurgery, curettage, and laser surgery, a local anesthetic is used to numb the skin before the procedure.
A wart may return after surgery because surgery removes the wart but does not destroy the virus that causes the wart. The type of surgery used to remove warts depends on their type, location, and size. Curettage, electrosurgery, and laser surgery are more likely than cryotherapy to leave scars and thus are usually reserved for hard-to-remove or recurring warts.
Nonsurgical treatments are less likely to cause scarring than surgical treatments. Scars that develop after surgery on the sole of the foot can be very painful. The pain from the surgical treatment usually comes from the injection of local anesthetic, not from the procedure itself. You may have pain after the drug wears off. Except for paring, all surgical treatments require anesthetic.
Plant medicine is a potent antiviral agent against warts. The antiviral properties of plant medicine make it have ability to penetrate all layers of the skin and enter the blood stream. It inhibits and kills the HPV virus, resulting in elimination of warts and wart like substances. The antiviral properties in plant medicine are highly pronounced and well documented.
When treating warts, plant medicine hits the infection hard and fast utilizing the powerful forces of its naturally occurring monoterpenes. These micro particles provide the most rapid absorption; they enter cell membranes with incredible swiftness and have a direct antiviral effect against warts. They quantifiably destroy the HPV virus, thus characterizing plant medicine as a potent antiwarts agent. To learn more, please go to http://www.naturespharma.org.
The etiology of oral epidermoide carcinoma is connected to the abusive use of tobacco and alcohol, having been in various studies demonstrated the effect synergetic of these
agents, the gastroesophageal reflux disease play role in pathogenesis of the Squamous cell carcinoma of the larynx.
Laryngeal cancer is the most common cancer of the upper aerodigestive tract. The incidence of laryngeal tumors is closely correlated with smoking, as head and neck tumors occur 6 times more often among cigarette smokers than among nonsmokers. The age-standardized risk of mortality from laryngeal cancer appears to have a linear relationship with increasing cigarette consumption. Death from laryngeal cancer is 20 times more likely for the heaviest smokers than for nonsmokers.
It should be suspected in any patient with hoarseness of the voice for three weeks or longer until proven otherwise.
Men are affected more often than women but during the last decade, the number of cases in women has increased such that they now account for about 20% of cases. Most patients are elderly and almost always, are smokers.
Sixty percent of tumours occur in the glottis and present early with dysphonia. If detected early, the prognosis is excellent with a 90% 5 year cure rate.